VICRYL* suture is a synthetic absorbable sterile surgical suture composed
of a copolymer made from 90% glycolide and 10% L-lactide. The empirical
formula of the copolymer is (C2H2O2)m(C3H4O2)n.
Braided VICRYL* sutures are coated with a mixture composed of equal
parts of copolymer of glycolide and lactide (Polyglactin 370) and calcium
stearate. Polyglactin 910 copolymer and Polyglactin 370 with calcium stearate
have been found to be nonantigenic, nonpyrogenic and elicit only a
slight tissue reaction during absorption.
VICRYL* sutures are dyed by adding D+C violet # 2 (Color Index number:
60725) during polymerisation. Sutures are also available in the undyed form.
VICRYL* is available in a range of gauge sizes and lengths, non-needled or
attached to stainless steel needles of varying types and sizes. The needles
may be attached permanently or as CR-needles (control release), enabling
the needles to be pulled off instead of being cut off. Combinations with needles
are available which are suitable for application in a magnetic field up to
1,5 tesla. The needles are bicolour (silver/black) and the labelling shows
MRI. Full details are contained in the catalogue.
VICRYL* complies with the requirements of the United States Pharmacopoeia
for Absorbable Surgical Suture and the European Pharmacopoeia for
Sterile Synthetic Absorbable Braided Sutures (except for an occasional slight
oversize in some gauges).
VICRYL* suture elicits a minimal initial inflammatory reaction in tissues and
ingrowth of fibrous connective tissue. Progressive loss of tensile strength
and eventual absorption of VICRYL* sutures occurs by means of hydrolysis,